Growing up, Kat Arney was always told by her mom that she wasn't creative—that she was destined to be a scientist instead, and after his father's unexpected death, Kevin McNulty becomes an investment banker, convinced it's the life his dad would have wanted for him.

Every time Billie Sainwood is intimate with a partner, she loses consciousness—a medical mystery that makes dating difficult, and Kelsea Best is sleepwalking through graduate school until an unexpected encounter with a postdoc at a brewery forces her to confront feelings she's spent a lifetime trying to ignore.

When Ryan Jones receives a DNA test from his mom for Christmas, he expects to learn a little more about his family history and heritage, and after years of unexplained headaches, Alicia Silver is finally diagnosed with multiple sclerosis—a discovery that leads to a family secret she never saw coming.

Catherine Macdonald always wanted to study sharks, but her first time tagging them in the field doesn't go as planned, and when Michelle Tong visits home after her first semester of medical school, a stranger presents an ethical dilemma.

Physicist Leslie Atkins has spent her life trusting evidence over intuition, and Eric Jankowski is determined to beat his math-genius dad at the game Go.

Kimberly Babiarz sets out to fight human trafficking, only to discover that one of the biggest obstacles is the lack of reliable data, and after years of therapy, Denise Cai believes she's moved beyond her trauma—until her family notices patterns she can't yet see.

Growing up in the fifties and sixties, Jenice Matias senses there's more to her mother's occupation than she understands, and D.B. Firstman has always known their body is different, but at the age of thirty, they make a discovery that changes everything.

After years of helping others safely navigate glaciers, Monte Montepare suddenly finds himself at the mercy of one and Jessica Lee Williamson's OCD fixates on a single question: how will she die?