A power outage on campus leads physics student Zoya Vallari to take a stand against her university's female-only curfew, and firefighter Nick Baskerville is eager to prove himself when he arrives on the scene of his first fire.

In the middle of a school day, science teacher Brittany Beck passes out in her classroom, leading her to reflect on what got her here, and inspired by her grandfather, Kitty Yang becomes a math teacher, but soon realizes she misses being a student.

As a brand-new professor of physiology, John Redden is eager to help students, but soon realizes it’s more complicated than he thought, and biologist Sarah Fankhauser’s relationship with her adviser changes when she joins her lab as a grad student.

Just before she leaves for her dream opportunity to teach marine science on the Red Sea, Latasha Wright gets a call that puts her plans in jeopardy, and growing up, Sheena Cruickshank's teenage older brother inspires her love of science, but then one summer he returns from university with a lump on his arm.

A question that Laura Spink asked her parents as a kid comes up again when her own child begins to ask similar questions, and after Denise Coberley brings up her doubt in the Bible to her adoptive religious parents, she finds herself on a journey of self-discovery.