After her father, a well-known intellectual, passes away, neurobiologist Eva Higginbotham tries to live up to his academic standards, and Nisse Greenberg travels home to care for his father after a brain injury.

Writer Alison Smith reconnects with her estranged father after he develops Alzheimer's disease, and science journalist Peter Brannen mourns the loss of his mother while studying the earth’s biggest mass extinction.

Growing up, Moni Avello struggles to understand her younger sister, who has Asperger's syndrome, and for Morgan Givens, the onset of puberty feels like an alien invasion. 

Chase Masterson's role on Star Trek Deep Space 9 inspires her to think about how she can help others, and Bethany Van Delft and her fiance reckon with the zombie apocalypse.

Growing up, Amanda Gorman is determined to eliminate her speech impediment, and as an aspiring scientist brought up in a family of artists, Elisa Schaum feels like a black sheep.